| 1857 | Harris Teachers College The St. Louis Board of Education founds Harris Teachers College to prepare white teachers for white elementary schools. |
| 1890 | Stowe Teachers College The St. Louis Board of Education founds Stowe Teachers College to prepare black teachers for black elementary schools. |
| 1938 | Both Colleges reorganize themselves and form two academic levels: a junior college division and a senior college division. |
| 1954 | Harris Teachers College The St. Louis Board of Education merges the two Colleges, which became Harris Teachers College. |
| 1977 | Harris-Stowe College The St. Louis Board of Education changes the name to Harris-Stowe College. |
| 1979 | The state of Missouri passes legislation that makes Harris-Stowe College a part of the state’s system of Public Higher Education. |
| 1981 | The state of Missouri approves baccalaureate degree programs in Early Childhood Education, Middle School Education and Urban Education. |
| 1987 | Historically Black College Harris-Stowe College is named one of the nation’s Historically Black Colleges and Universities under the U.S. Department of Education. |
| 1993 | Harris-Stowe State College The state of Missouri authorizes the College to expand its mission by offering baccalaureate degree programs in Business Administration, Secondary Teacher Education and Criminal Justice, as well as to add the word “state” to its title. |
| 1996 | The city of St. Louis gives the college nearly 18 acres of land, formerly Laclede Town site, for just $10. |
| 1998 | AT&T Library and Technology Resource Center Construction of this building, formerly the Southwestern Bell Library and Technology Resource Center, begins. |
| 1999 | Vashon Community Center Harris-Stowe receives the Vashon Community Center and its land for just $10 from the city of St. Louis. |
| 2003 | Emerson Performance Center The College completes its fourth building, which houses the Board of Regents Gymnasium, the Bank of America Theatre and the Whitaker Foundation Art Room. |
| 2004 | US Bank Entryway Arch The College dedicates its new arch, emblematic of the great things that occur when you enter the arches. |
| 2005 | The Anheuser-Busch School of Business opens in a temporary facility in the fall of 2005. On August 26, the College celebrates its official change to Harris-Stowe State University, and the former Vashon Community Center facility is officially listed by the Federal Government in the National Register of Historic Places. |
| 2006 | Rev. Dr. William G. Gillespie Residence Hall and Student Center Harris-Stowe State University becomes a residential campus with the opening of its first-ever residence hall. |
| 2009 | Harris-Stowe opens the state-of-the-art William L. Clay, Sr. Early Childhood Development/Parenting Education Center on its campus. |
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2010
2011
2011 |
Harris-Stowe breaks ground on its second residence hall and adds two new degree programs, Mathematics and Biology.
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